Patient information leaflet

for Russia only

Indications for the use of medicinal product Enterosgel

Registration number: P N003719/02-19.07.2016.

Trade name: Enterosgel®.

Generic name: polymethylsiloxane polyhydrate.

Chemical name: product of nonlinear polycondensation of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate.

Description: Homogeneous paste-like mass from white to almost white colour, odourless.


100 g of the product contain:
Active ingredient:
Polymethylsiloxane polyhydrate 70 g
Purified water 30 g

Pharmacotherapeutic group:
intestinal adsorbent.

ATC Code: A07B.

Pharmacological properties

Enterosgel® has a porous structure of hydrophobic organic silicon matrix (molecular sponge) that sorbs mostly medium molecular toxic metabolites (m.m. 70 - 1000). The medicinal product has pronounced sorption and detoxification properties. In the intestinal lumen, it binds endogenous and exogenous toxic substances of various nature, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, salts of heavy metals, radionuclides, alcohol and removes them from the body. Enterosgel® also sorbs some metabolic waste, including excess bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for endogenous toxicosis. Enterosgel® does not reduce absorption of vitamins and trace elements, it helps restore the damaged intestinal microflora. Enterosgel® does not affect gastrointestinal motor function.


Enterosgel® is not absorbed in the gastrointestinal tract, it is excreted unchanged in 12 hours.

Therapeutic indications

In adults and children as a detoxification agent:


Individual intolerance to the medicinal product, intestinal atony.

Use in pregnancy and lactation

Enterosgel® is not contraindicated in pregnancy and lactation.

Dosage and method of administration

Take Enterosgel ® orally 1-2 hours before or 1-2 hours after a meal or intake of other medicines.

Take with water.

Stir the necessary amount of the medicinal product in a glass of water (ratio 1:3) at room temperature and drink the mixture, or take the medicinal product orally and wash it down with water.

Adverse reactions

May cause nausea, constipation. In a condition of severe renal and/or liver failure, aversion towards the medicinal product may appear.


No cases of overdose were reported.

Interaction with other medicinal products

Simultaneous intake of Enterosgel® with other medicines may reduce absorption of the latter.

Special indications and precautions for use

Enterosgel® can be used in complex therapy with other drugs, provided a time interval of 1-2 hours is observed before or after intake of other medicinal products.

Effect on ability to drive and operate machinery

Enterosgel® showed no effects on the ability to drive and operate machinery.

Pharmaceutical form

Paste for oral administration.

22.5 g sachets of composite two-layer material on the basis of aluminum foil and film.

10 sachets 22.5 g each, and Patient Information Leaflet are placed in a cardboard package.

Storage conditions

Store at temperatures not below 4°C and not above 30°C. Keep out of the reach of children. Protect from drying after opening the package.

Protect from freezing.

Shelf life

3 years. Do not use after the expiry date printed on the package.

Dispensing conditions

Over the counter.



32/2, L.Tolstoy str., Dankov, Lipetsk reg., 399851, Russia

Tel./fax: +7 (495) 223-91-00,, e-mail:

Name and address of marketing authorisation holder:


office 5, room I, floor 1, bdg 2, bulk 1, 50, Shipilovskaya str., Moscow, 115573, Russia

Tel./fax: +7 (499) 782-61-96,, e-mail:

Claiming organisation:


bdg 2, bulk 1, 50, Shipilovskaya str., Moscow, 115573, Russia

Tel./fax: +7 (495) 223-91-00,, e-mail: